Article
Maternal and paternal chromosomes 7 show differential methylation of many genes in lymphoblast DNA.
Genomics - 1 Apr 2001
Hannula K, Lipsanen-Nyman M, Scherer S W, Holmberg C, Höglund P, Kere J
Abstract excerpt
Genomic imprinting, the differential expression of paternal and maternal alleles, involves many chromosomal regions and plays a role in development and growth. Differential methylation of maternal and paternal alleles is a hallmark of imprinted genes, and thus methylation assays are widely used to support the identification of novel imprinted genes. Either blood or lymphoblast DNAs are most often used in these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
