Article
Genome-wide assessment of imprinted expression in human cells.
Genome biology - 1 Jan 2011
Morcos Lisanne, Ge Bing, Koka Vonda, Lam Kevin C L, Pokholok Dmitry K, Gunderson Kevin L, Montpetit Alexandre, Verlaan Dominique J, Pastinen Tomi
Abstract excerpt
BACKGROUND: Parent-of-origin-dependent expression of alleles, imprinting, has been suggested to impact a substantial proportion of mammalian genes. Its discovery requires allele-specific detection of expressed transcripts, but in some cases detected allelic expression bias has been interpreted as imprinting without demonstrating compatible transmission patterns and excluding heritable variation. Therefore, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
