Article
Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase.
Biochemical and biophysical research communications - 11 May 2001
Comtesse N, Maldener E, Meese E
Abstract excerpt
MGEA5 was originally identified to be a novel human hyaluronidase, which is immunogenic in meningioma patients. Recently an N-acetylglucosaminidase was reported with identical sequence. Here, we define the origin of a splice variant by determining the genomic organization of the mgea5 gene. We find the splice variant missing a putative acetyltransferase domain of MGEA5. As for evolutionary analysis, we show that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.