Article
Novel immunogenic antigen homologous to hyaluronidase in meningioma.
Human molecular genetics - 1 Nov 1998
Heckel D, Comtesse N, Brass N, Blin N, Zang K D, Meese E
Abstract excerpt
By screening a meningioma expression library with autologous serum we identified four cDNA clones representing a novel gene with striking homology to Caenorhabditis elegans hyaluronidase as indicated by BLASTP analysis. In humans hyaluronidase has been implicated in cancer development and three h...
Topics
- Acetylglucosaminidase
- Alternative Splicing
- Amino Acid Sequence
- Antigens, Neoplasm
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 10
- DNA, Complementary
- Evolution, Molecular
- Genetic Variation
- Histone Acetyltransferases
- Humans
- Hyaluronoglucosaminidase
- In Situ Hybridization, Fluorescence
- Meningioma
- Molecular Sequence Data
- Neoplasm Proteins
- Open Reading Frames
