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Article

Misexpression of Xsiah-2 induces a small eye phenotype in Xenopus.

Mechanisms of development - 1 May 2001

Bogdan S, Senkel S, Esser F, Ryffel G U, Pogge v Strandmann E

Abstract excerpt

Recent data demonstrate a structural and functional conservation of factors crucial for the development of the insect and the vertebrate eye. We isolated Xenopus siah-2, a protein with 67% identity to Drosophila sina (seven in absentia) and 85% identity to the mouse and human siah-2 proteins. Sina is required in Drosophila for the R7 photoreceptor cell formation during eye development, because it down regulates...

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PMID: 11335112
DOI: 10.1016/s0925-4773(01)00332-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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