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Article

Pharmacological characterization of homobaclofen on wild type and mutant GABA(B)1b receptors coexpressed with the GABA(B)2 receptor.

European journal of pharmacology - 13 Apr 2001

Jensen A A, Madsen B E, Krogsgaard-Larsen P, Bräuner-Osborne H

Abstract excerpt

Homobaclofen (5-amino-3-(4-chlorophenyl) pentanoic acid) is a homologue of the classical GABA(B) receptor agonist baclofen. In a recent study, the two enantiomers of this compound were tested in a GABA(B) receptor selective [3H]gamma-aminobutyric acid ([3H]GABA) binding assay using rat brain homogenate and in an assay of electrically induced contractions of guinea pig ileum. The results from the two tissues did,...

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PMID: 11334848
DOI: 10.1016/s0014-2999(01)00918-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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