Article
Phenotypic consequences of lung-specific inducible expression of FGF-3.
Proceedings of the National Academy of Sciences of the United States of America - 8 May 2001
Zhao B, Chua S S, Burcin M M, Reynolds S D, Stripp B R, Edwards R A, Finegold M J, Tsai S Y, DeMayo F J
Abstract excerpt
Members of the fibroblast growth factor (FGF) family play a critical role in embryonic lung development and adult lung physiology. The in vivo investigation of the role FGFs play in the adult lung has been hampered because the constitutive pulmonary expression of these factors often has deleterious effects and frequently results in neonatal lethality. To circumvent these shortcomings, we expressed FGF-3 in the...
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