Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of various genotype characteristics for inosine accumulation in Escherichia coli W3110.

Bioscience, biotechnology, and biochemistry - 1 Mar 2001

Matsui H, Kawasaki H, Shimaoka M, Kurahashi O

Abstract excerpt

For the derivation of an inosine-overproducing strain from the wild type microorganism, it is known that the addition of an adenine requirement, removal of purine nucleoside hydrolyzing activity, removal of the feedback inhibition, and repression of key enzymes in the purine nucleotides biosynthetic pathway are essential. Thus, the disruption of purA (adenine requirement), deoD (removal of purine nucleosides...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Deaminase
Share to Bacterial Proteins
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli Proteins

Share to Inosine

Share to Mutagenesis, Site-Directed

Share to Purine-Nucleoside Phosphorylase

Share to Repressor Proteins

Source

Identifiers

PMID: 11330670
DOI: 10.1271/bbb.65.570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of various genotype characteristics for inosine accumulation in Escherichia coli W3110.PMID 11330670Read ↗

gsk disruption leads to guanosine accumulation in Escherichia coli.Semantic proximity Read ↗

Effect of amplification of desensitized purF and prs on inosine accumulation in Escherichia coli.Semantic proximity Read ↗

Effects of edd and pgi disruptions on inosine accumulation in Escherichia coli.Semantic proximity Read ↗

Accumulation of gene-targeted Bacillus subtilis mutations that enhance fermentative inosine production.Semantic proximity Read ↗

Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains.Semantic proximity Read ↗

Deregulation of purine pathway in Bacillus subtilis and its use in riboflavin biosynthesis.Semantic proximity Read ↗

[Studies of gene regulation of de novo biosynthetic pathway of purine in Salmonella typhimurium. X. Isolation of purR(am) mutants and preliminary studies of amino acid substitution].Semantic proximity Read ↗

Adenine deaminase activity of the yicP gene product of Escherichia coli.Semantic proximity Read ↗

Complete deficiency of 5'-nucleotidase activity in Escherichia coli leads to loss of growth on purine nucleotides but not of their excretion.Semantic proximity Read ↗

The derepression of enzymes of de novo pyrimidine biosynthesis pathway in Brevibacterium ammoniagenes producing uridine-5-monophosphate and uracil.Semantic proximity Read ↗

De novo engineering and metabolic flux analysis of inosine biosynthesis in Bacillus subtilis.Semantic proximity Read ↗

[Adenine effect on the biosynthesis of 5'-inosinic acid by the mutant Brevibacterium ammoniagenes 225-5].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.