The derepression of enzymes of de novo pyrimidine biosynthesis pathway in Brevibacterium ammoniagenes producing uridine-5-monophosphate and uracil.

doi:10.1016/0378-1097(91)90271-b

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Article

The derepression of enzymes of de novo pyrimidine biosynthesis pathway in Brevibacterium ammoniagenes producing uridine-5-monophosphate and uracil.

FEMS microbiology letters - 15 Aug 1991

Nudler A A, Garibyan A G, Bourd G I

Abstract excerpt

A mutant of Brevibacterium ammoniagenes producing large quantities of UMP and uracil is described. The mutations render bacteria braditrophic for arginine, sensitive to adenine, resistant to rifampicin and pyrimidine analogues 5-fluorouracil, 5-fluorouridine, azauracil and thiouracil. The activit...

Topics

Brevibacterium
DNA-Directed RNA Polymerases
Gene Expression Regulation, Bacterial
Mutation
Pyrimidines
Uracil
Uridine Monophosphate

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