Article
A novel role for ecdysone in Drosophila conditioned behavior: linking GPCR-mediated non-canonical steroid action to cAMP signaling in the adult brain.
PLoS genetics - 1 Jan 2013
Ishimoto Hiroshi, Wang Zhe, Rao Yi, Wu Chun-Fang, Kitamoto Toshihiro
Abstract excerpt
The biological actions of steroid hormones are mediated primarily by their cognate nuclear receptors, which serve as steroid-dependent transcription factors. However, steroids can also execute their functions by modulating intracellular signaling cascades rapidly and independently of transcriptional regulation. Despite the potential significance of such "non-genomic" steroid actions, their biological roles and...
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