Article
Uncoupling protein 1 and 3 polymorphisms are associated with waist-to-hip ratio.
Journal of molecular medicine (Berlin, Germany) - 1 May 2003
Herrmann Stefan-Martin, Wang Ji-Guang, Staessen Jan A, Kertmen Ercan, Schmidt-Petersen Klaus, Zidek Walter, Paul Martin, Brand Eva
Abstract excerpt
Body weight regulation is a complex phenotype also depending on the action of uncoupling proteins (UCPs) that mediate the "uncoupling" of respiration leading to the dissipation of energy as heat. This study investigated whether genetic variants in the genes encoding UCP-1 and UCP-3 are associated with different obesity-related phenotypes in 162 whites with a wide range of body mass index. All subjects were...
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