Article
SopE acts as an Rab5-specific nucleotide exchange factor and recruits non-prenylated Rab5 on Salmonella-containing phagosomes to promote fusion with early endosomes.
The Journal of biological chemistry - 29 Jun 2001
Mukherjee K, Parashuraman S, Raje M, Mukhopadhyay A
Abstract excerpt
Rab-GTPase regulates the fusion between two specific vesicles. It is well documented that, for their biological function, Rab proteins need to be prenylated for attachment to the vesicle membrane. In contrast, we showed in the present investigation that SopE, a type III secretory protein of Salmo...
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