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Article

Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance.

Oncogene - 15 Mar 2001

Turton N J, Judah D J, Riley J, Davies R, Lipson D, Styles J A, Smith A G, Gant T W

Abstract excerpt

The multidrug resistance (MDR) phenotype is a major cause of cancer treatment failure. Here the expressions of 4224 genes were analysed for association with intrinsic or acquired doxorubicin (DOX) resistance. A cluster of overexpressed genes related to DOX resistance was observed. Included in this cluster was ABCB1 the P-glycoprotein transporter protein gene and MMP1 (Matrix Metalloproteinase 1), indicative of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11313874
DOI: 10.1038/sj.onc.1204235

Genes

ABCB1
ABCB4
MMP1
OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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