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Article

Chemotherapy-induced tumor gene expression changes in human breast cancers

19 Feb 2009

Abstract excerpt

OBJECTIVE: Studying chemotherapy-induced gene expression changes in vivo, which could provide insights into mechanisms of chemotherapy resistance. METHODS: We analyzed and compared tumor gene expression changes of about 38 500 genes before and 3 weeks after doxorubicin or docetaxel treatment in 47 breast cancer patients. RESULTS: By using the median expression level of each probe set as the parameter, less than...

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PMID: 19352302
DOI: 10.1097/fpc.0b013e32831ebb5d

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