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Article

Effect of genotyping error on type-I error rate of affected sib pair studies with genotyped parents.

Human heredity - 1 Jan 2005

Seaman S R, Holmans P

Abstract excerpt

OBJECTIVE: In affected sib pair studies without genotyped parents the effect of genotyping error is generally to reduce the type I error rate and power of tests for linkage. The effect of genotyping error when parents have been genotyped is unknown. We investigated the type I error rate of the single-point Mean test for studies in which genotypes of both parents are available. METHODS: Datasets were simulated...

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PMID: 15925894
DOI: 10.1159/000085939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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