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Article

Analysis of the molecular species generated by MDM2 gene amplification in liposarcomas.

International journal of cancer - 15 Jun 2001

Tamborini E, Della Torre G, Lavarino C, Azzarelli A, Carpinelli P, Pierotti M A, Pilotti S

Abstract excerpt

MDM2 gene is overexpressed in several tumors and its product may be processed into different isoforms, some of which have been demonstrated to possess transforming activity. In a panel of liposarcomas characterized by displaying 4 different combinations of mdm2/p53 immunoreactivity, molecular analysis of amplified MDM2 gene revealed a coexistence of mutated full-length MDM2 messenger RNAs, an out-of-frame...

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Source

Identifiers

PMID: 11351297
DOI: 10.1002/ijc.1271

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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