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Desmoid Fibromatosis With TP53 Mutation and Striking Nuclear Pleomorphism.

International journal of surgical pathology - 1 Dec 2023

Foster Charlotte R, Strauss Magreet, Hornick Jason L, Habeeb Omar

Abstract excerpt

Desmoid fibromatosis is a myofibroblastic neoplasm of intermediate biologic potential, which has a strong predilection for local recurrence but does not metastasize. Arranged in long, sweeping fascicles with infiltrative borders, desmoid fibromatosis typically consists of uniform, bland myofibroblastic spindle cells that harbor mutation of CTNNB1 (or less often APC). In this report, we present a remarkable case...

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PMID: 36908221
DOI: 10.1177/10668969231160255

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