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Article

Histologic variability in solitary fibrous tumors reflects angiogenic and growth factor signaling pathway alterations.

Human pathology - 1 Jul 2015

Demicco Elizabeth G, Wani Khalida, Fox Patricia S, Bassett Roland L, Young Eric D, Lev Dina, Aldape Kenneth D, Lazar Alexander J, Wang Wei-Lien

Abstract excerpt

This study aimed to evaluate expression of receptor tyrosine kinases, their ligands, and mutational status in solitary fibrous tumors, with correlation to histopathologic variants, tumor stage, and aggressive behavior. Immunohistochemical staining for PDGFα; PDGFβ; PDGFR-α; PDGFR-β; IGF1R; EGFR;...

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Share to Angiogenic Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Intercellular Signaling Peptides and Proteins

Share to Neovascularization, Pathologic

Share to Tissue Array Analysis

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Source

Identifiers

PMID: 25976141
DOI: 10.1016/j.humpath.2015.03.014

Genes

EGFR
IGF2
MET
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25976141-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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