Article
Fibroblast phenotype plasticity: relevance for understanding heterogeneity in "fibroblastic" tumors.
Ultrastructural pathology - 1 Jan 2000
Eyden Brian
Abstract excerpt
Cellular transformations, reflecting phenotypic plasticity, characterize embryonic life, would-repair, physiological adaptation, and neoplasia. Fibroblastic tumors show a range of cellular differentiation, which can be rationalized in terms of phenotypic plasticity of the "normal" fibroblast. In this paper, the various kinds of fibroblast transformation are discussed, and some insights provided into the molecular...
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