Article
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
Cell - 6 Apr 2001
Cantor S B, Bell D W, Ganesan S, Kass E M, Drapkin R, Grossman S, Wahrer D C, Sgroi D C, Lane W S, Haber D A, Livingston D M
Abstract excerpt
BRCA1 interacts in vivo with a novel protein, BACH1, a member of the DEAH helicase family. BACH1 binds directly to the BRCT repeats of BRCA1. A BACH1 derivative, bearing a mutation in a residue that was essential for catalytic function in other helicases, interfered with normal double-strand brea...
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