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Article

Mutation analysis of BRIP1/BACH1 in BRCA1/BRCA2 negative Chinese women with early onset breast cancer or affected relatives.

Breast cancer research and treatment - 1 May 2009

Cao A-Yong, Huang Juan, Hu Zhen, Li Wen-Feng, Ma Zhong-Liang, Tang Li-Li, Zhang Bin, Su Feng-Xi, Zhou Jie, Di Gen-Hong, Shen Kun-Wei, Wu Jiong, Lu Jin-Song, Luo Jian-Min, Yuan Wen-Tao, Shen Zhen-Zhou, Huang Wei, Shao Zhi-Ming

Abstract excerpt

The proper interaction between BRIP1/BACH1 and BRCA1 protein has been found to be crucial for BRCA1-mediated DNA double-strand break repair and BRIP1/BACH1 mutations were estimated to confer a relative risk for breast cancer of 2.0 in western populations. In Chinese population, BRCA1 mutations could explain a relatively large proportion of inherited breast cancer cases in comparison with BRCA2 mutations, which...

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Source

Identifiers

PMID: 18483852
DOI: 10.1007/s10549-008-0052-z

Genes

BACH1
BRCA1
BRIP1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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