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Article

Bach1: Function, Regulation, and Involvement in Disease

1 Jan 2018

Abstract excerpt

The transcription factor BTB and CNC homology 1 (Bach1) is widely expressed in most mammalian tissues and functions primarily as a transcriptional suppressor by heterodimerizing with small Maf proteins and binding to Maf recognition elements in the promoters of targeted genes. It has a key regulatory role in the production of reactive oxygen species, cell cycle, heme homeostasis, hematopoiesis, and immunity and...

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Identifiers

PMID: 30370001
DOI: 10.1155/2018/1347969

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