Article
Genetic dissection of the yeast 26S proteasome: cell cycle defects caused by the Deltarpn9 mutation.
Biochimie - 1 Jan 2000
Takeuchi J, Toh-e A
Abstract excerpt
Rpn9 is one of the subunits of the regulatory particle of the yeast 26S proteasome and is needed for stability or efficient assembly of the 26S proteasome. As anticipated from the fact that the rpn9 disruptant grew at 25 degrees C but arrested in G2/M phase at 37 degrees C, the CDK inhibitor Sic1p was found to be degraded at the G1/S boundary in the Deltarpn9 cells. The degradation of the anaphase inhibitor Pds1p...
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