Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of hilC and hilD in regulation of hilA expression in Salmonella enterica serovar Typhimurium.

Journal of bacteriology - 1 May 2001

Lucas R L, Lee C A

Abstract excerpt

Sequences between -332 and -39 upstream of the hilA promoter are required for repression of hilA. An unidentified repressor is thought to bind these upstream repressing sequences (URS) to inhibit hilA expression. Two AraC-like transcriptional regulators encoded on Salmonella pathogenicity island 1 (SPI1), HilC and HilD, bind to the URS to counteract the repression of hilA. The URS is required for regulation of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Outer Membrane Proteins
Share to Down-Regulation
Share to Genes, Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multienzyme Complexes

Share to Osmolar Concentration

Share to Protein Kinases

Share to Salmonella typhimurium

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 11292791
DOI: 10.1128/JB.183.9.2733-2745.2001
PMCID: PMC99488

Genes

SPI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of hilC and hilD in regulation of hilA expression in Salmonella enterica serovar Typhimurium.PMID 11292791Read ↗

Two AraC/XylS family members can independently counteract the effect of repressing sequences upstream of the hilA promoter.Semantic proximity Read ↗

Transcription of theSalmonellaInvasion Gene Activator,hilA, Requires HilD Activation in the Absence of Negative RegulatorsSemantic proximity Read ↗

HilE Interacts with HilD and Negatively Regulates hilA Transcription and Expression of the Salmonella enterica Serovar Typhimurium Invasive PhenotypeSemantic proximity Read ↗

AraC/XylS family members, HilD and HilC, directly activate virulence gene expression independently of HilA in Salmonella typhimuriumSemantic proximity Read ↗

HilE Regulates HilD by Blocking DNA Binding in Salmonella enterica Serovar Typhimurium.Semantic proximity Read ↗

Identification and characterization of mutants with increased expression of hilA, the invasion gene transcriptional activator of Salmonella typhimurium.Semantic proximity Read ↗

HilD, HilC, and RtsA Form Homodimers and Heterodimers To Regulate Expression of the Salmonella Pathogenicity Island I Type III Secretion SystemSemantic proximity Read ↗

The HilA Box and Sequences outside It Determine the Magnitude of HilA-Dependent Activation of P prgH from Salmonella Pathogenicity Island 1Semantic proximity Read ↗

Degradation of the HilC and HilD regulator proteins by ATP-dependent Lon protease leads to downregulation of Salmonella pathogenicity island 1 gene expression.Semantic proximity Read ↗

Delineation of the Salmonella enterica serovar Typhimurium HilA regulon through genome-wide location and transcript analysis.Semantic proximity Read ↗

Mlc regulation of Salmonella pathogenicity island I gene expression via hilE repression.Semantic proximity Read ↗

An incoherent feedforward loop formed by SirA/BarA, HilE and HilD is involved in controlling the growth cost of virulence factor expression by Salmonella Typhimurium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.