Article
Delineation of the Salmonella enterica serovar Typhimurium HilA regulon through genome-wide location and transcript analysis.
Journal of bacteriology - 1 Jul 2007
Thijs Inge M V, De Keersmaecker Sigrid C J, Fadda Abeer, Engelen Kristof, Zhao Hui, McClelland Michael, Marchal Kathleen, Vanderleyden Jos
Abstract excerpt
The Salmonella enterica serovar Typhimurium HilA protein is the key regulator for the invasion of epithelial cells. By a combination of genome-wide location and transcript analysis, the HilA-dependent regulon has been delineated. Under invasion-inducing conditions, HilA binds to most of the known target genes and a number of new target genes. The sopB, sopE, and sopA genes, encoding effector proteins secreted by...
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