Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of mutants with increased expression of hilA, the invasion gene transcriptional activator of Salmonella typhimurium.

FEMS immunology and medical microbiology - 1 May 2000

Fahlen T F, Mathur N, Jones B D

Abstract excerpt

Induction of invasion gene transcription and expression of the invasive phenotype of Salmonella strains are regulated by environmental conditions. Experimental evidence indicates that oxygen, pH, and osmotic conditions need to closely resemble those of the host intestinal lumen for invasion gene activation. The hilA gene, encoded on Salmonella pathogenicity island 1 (SPI-1), is a transcriptional activator which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Culture Media
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Lac Operon

Share to Mutagenesis, Insertional

Share to Salmonella typhimurium

Share to Trans-Activators

Share to Transcriptional Activation

Source

Identifiers

PMID: 10767604
DOI: 10.1111/j.1574-695X.2000.tb01453.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of mutants with increased expression of hilA, the invasion gene transcriptional activator of Salmonella typhimurium.PMID 10767604Read ↗

Two AraC/XylS family members can independently counteract the effect of repressing sequences upstream of the hilA promoter.Semantic proximity Read ↗

Hha is a negative modulator of transcription of hilA, the Salmonella enterica serovar Typhimurium invasion gene transcriptional activator.Semantic proximity Read ↗

Mutations influencing expression of the Salmonella enterica serovar Enteritidis pathogenicity island I key regulator hilA.Semantic proximity Read ↗

HilE Interacts with HilD and Negatively Regulates hilA Transcription and Expression of the Salmonella enterica Serovar Typhimurium Invasive PhenotypeSemantic proximity Read ↗

Delineation of the Salmonella enterica serovar Typhimurium HilA regulon through genome-wide location and transcript analysis.Semantic proximity Read ↗

Roles of hilC and hilD in regulation of hilA expression in Salmonella enterica serovar Typhimurium.Semantic proximity Read ↗

AraC/XylS family members, HilD and HilC, directly activate virulence gene expression independently of HilA in Salmonella typhimuriumSemantic proximity Read ↗

The ATP-dependent lon protease of Salmonella enterica serovar Typhimurium regulates invasion and expression of genes carried on Salmonella pathogenicity island 1.Semantic proximity Read ↗

Transcription of theSalmonellaInvasion Gene Activator,hilA, Requires HilD Activation in the Absence of Negative RegulatorsSemantic proximity Read ↗

The HilA Box and Sequences outside It Determine the Magnitude of HilA-Dependent Activation of P prgH from Salmonella Pathogenicity Island 1Semantic proximity Read ↗

A HilA-independent pathway to Salmonella typhimurium invasion gene transcription.Semantic proximity Read ↗

Lon Protease Activity Causes Down-Regulation of Salmonella Pathogenicity Island 1 Invasion Gene Expression after Infection of Epithelial CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.