Article
Mlc regulation of Salmonella pathogenicity island I gene expression via hilE repression.
Nucleic acids research - 1 Jan 2007
Lim Sangyong, Yun Jiae, Yoon Hyunjin, Park Chehwee, Kim Boowon, Jeon Byeonghwa, Kim Dongho, Ryu Sangryeol
Abstract excerpt
The global regulator Mlc is a repressor of several genes and operons that are involved in sugar uptake and metabolism. A Salmonella enterica serovar Typhimurium mlc mutant showed reduced levels of invasion and cytotoxicity compared to the wild-type, and exhibited reduced expression levels of hilD, hilA and invF, which are regulatory genes in the Salmonella pathogenicity island 1 (SPI1). However, the effects of...
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