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Article

Cultured glial cells are resistant to the effects of motor neurone disease-associated SOD1 mutations.

Neuroscience letters - 20 Apr 2001

Williams R E, Cookson M R, Fray A E, Manning P M, Menzies F M, Figlewicz D A, Shaw P J

Abstract excerpt

Free radical damage has been implicated in the pathophysiology of motor neurone disease (MND); mutations have been identified in the gene encoding Cu/Zn superoxide dismutase (SOD1). There is evidence that glial cell dysfunction may contribute to motor neurone injury, but the exact role of glial c...

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Source

Identifiers

PMID: 11290408
DOI: 10.1016/s0304-3940(01)01686-x

Genes

SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11290408-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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