Article
Influence of smokeless tobacco exposure on detoxification status and chromosomal damage in male and female habitues.
Mutation research - 5 Apr 2001
Mahimkar M B, Buch S C, Samant T A, Kapoor M D, Bhisey R A
Abstract excerpt
In India, a large number of tobacco chewers and masheri users are chronically exposed to tobacco genotoxicants. Detoxification processes involving cellular glutathione (GSH) and glutathione S-transferases (GST) determine the outcome of exposure to environmental mutagens including those present in tobacco. Hence, in this study, GSH levels, GST activity, GSTM1 genotype and cytogenetic damage were determined using...
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