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Article

Influence of glutathione S-transferase polymorphisms on genotoxic effects induced by tobacco smoke.

Mutation research - 1 Sept 2007

Palma Selena, Cornetta Tommaso, Padua Luca, Cozzi Renata, Appolloni Massimo, Ievoli Elena, Testa Antonella

Abstract excerpt

Genotoxicity of tobacco smoke has long been investigated and tobacco smoke is considered to be one of the principal human carcinogens. Although its role in DNA-damage induction and cancer development has been documented, the mechanisms by which this happens are not well understood. Many chemical constituents of tobacco smoke are enzymatically metabolized by phase-I and phase-II enzymes, but modifications in...

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Source

Identifiers

PMID: 17644396
DOI: 10.1016/j.mrgentox.2007.03.014

Genes

GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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