Article
Genotoxic biomonitoring of tobacco farmers: Biomarkers of exposure, of early biological effects and of susceptibility.
Journal of hazardous materials - 30 Jul 2012
Da Silva Fernanda Rabaioli, Da Silva Juliana, Allgayer Mariangela da C, Simon Caroline F, Dias Johnny F, dos Santos Carla E I, Salvador Mirian, Branco Catia, Schneider Nayê Balzan, Kahl Vivian, Rohr Paula, Kvitko Kátia
Abstract excerpt
Tobacco farming presents several hazards to those who cultivate and harvest the plant. The genotoxic and mutagenic effects in tobacco farmers were investigated. In order to verify the relationship between genetic susceptibility and biomarkers GSTT1, GSTM1, GSTP1, CYP2A6, PON, OGG1, RAD51, XRCC1, and XRCC4 genes polymorphism were evaluated. Oxidative stress markers and trace elements content were determined....
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