Article
GSTM1, GSTM3 and GSTT1 gene variants and risk of benign prostate hyperplasia in North India.
Disease markers - 1 Jan 2009
Mittal Rama Devi, Kesarwani Pravin, Singh Ranjana, Ahirwar Dinesh, Mandhani Anil
Abstract excerpt
Glutathione S-transferases (GSTs) play an important role in detoxification of various toxic compounds like carcinogens in cigarette smoke and tobacco by conjugating to toxic compounds and inactivating their hazardous effect. Variation in Glutathione S-Transferases (GSTs) genes may alter the catalytic efficiency of GST isoenzymes leading to potential increase in cancer susceptibility due to various carcinogens. We...
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