Article
A novel polymorphism in the promoter of the RAGE gene is associated with non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 2001
Schenk S, Schraml P, Bendik I, Ludwig C U
Abstract excerpt
The receptor for advanced glycosylation endproducts (RAGE) is abundant at both the transcriptional and translational level in normal lung but is not expressed in non-small cell lung cancer (NSCLC). In order to determine whether sequence variations might be responsible for the inactivation of RAGE in NSCLC, we investigated the RAGE gene in primary NSCLCs and in the corresponding normal tissues of nine patients....
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