Article
RAGE genetic polymorphisms are associated with risk, chemotherapy response and prognosis in patients with advanced NSCLC.
PloS one - 1 Jan 2012
Wang Xiang, Cui Enhai, Zeng Huazong, Hua Feng, Wang Bin, Mao Wei, Feng Xueren
Abstract excerpt
AIM: To explore the association between genetic polymorphisms of the receptor for advanced glycation end-products (RAGE) and susceptibility, chemotherapy response rate and prognosis of non-small cell lung cancer (NSCLC). METHOD: This is a prospective study in which 562 patients with NSCLC and 764 healthy controls were enrolled. Three RAGE genetic polymorphisms, namely, -429T/C, -374T/A and 82G/S were genotyped....
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