Article
The yeast plasma membrane protein Alr1 controls Mg2+ homeostasis and is subject to Mg2+-dependent control of its synthesis and degradation.
The Journal of biological chemistry - 11 May 2001
Graschopf A, Stadler J A, Hoellerer M K, Eder S, Sieghardt M, Kohlwein S D, Schweyen R J
Abstract excerpt
The Saccharomyces cerevisiae ALR1 (YOL130w) gene product Alr1p is the first known candidate for a Mg(2+) transport system in eukaryotic cells and is distantly related to the bacterial CorA Mg(2+) transporter family. Here we provide the first experimental evidence for the location of Alr1p in the yeast plasma membrane and for the tight control of its expression and turnover by Mg(2+). Using well characterized npi1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.