Elevated cytosolic free Ca2+ concentrations and massive Ca2+ accumulation within vacuoles, in yeast mutant lacking PMR1, a homolog of Ca2+ -ATPase.

doi:10.1016/0014-5793(96)00799-5

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Article

Elevated cytosolic free Ca2+ concentrations and massive Ca2+ accumulation within vacuoles, in yeast mutant lacking PMR1, a homolog of Ca2+ -ATPase.

FEBS letters - 26 Aug 1996

Halachmi D, Eilam Y

Abstract excerpt

The Ca2+ -ATPase homolog of Saccharomyces cerevisiae, PMR1, cloned by Rudolph et al. (Cell 58 (1989) 133-145) is required for normal Golgi functions. We have investigated the role of Pmr1-protein in maintaining homeostasis of cytosolic free Ca2+ concentration ([Ca2+]i). It was found that exposure...

Topics

Calcium
Calcium-Transporting ATPases
Cytosol
Ion Transport
Magnesium
Mutation
Saccharomyces cerevisiae
Vacuoles

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