Article
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.
The Journal of biological chemistry - 27 Apr 2001
Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, Tohyama M
Abstract excerpt
When accumulation of a malfolded protein in the endoplastic reticulum (ER) is induced by various adverse conditions, such as hypoxia, glucose starvation, and perturbation of calcium homeostasis, cells respond to the stress by increasing transcription of genes encoding ER molecular chaperones, a p...
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