Article
Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1.
Molecular and cellular biology - 1 Nov 2014
Gade Padmaja, Manjegowda Srikanta B, Nallar Shreeram C, Maachani Uday B, Cross Alan S, Kalvakolanu Dhananjaya V
Abstract excerpt
The death-associated protein kinase 1 (DAPK1) is an important regulator of cell death and autophagy. Recently, we have identified that ATF6, an endoplasmic reticulum-resident transcription factor, in association with the transcription factor CEBP-β, regulates the gamma interferon (IFN-γ)-induced expression of Dapk1 (P. Gade et al., Proc. Natl. Acad. Sci. U. S. A. 109:10316-10321, 2012,...
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