Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tip60 is a cell-type-specific transcriptional regulator.

Journal of biochemistry - 1 Apr 2001

Hlubek F, Löhberg C, Meiler J, Jung A, Kirchner T, Brabletz T

Abstract excerpt

Tip60 was originally identified as cellular HIV-Tat interacting protein and has been shown to augment Tat-dependent transcription. It has also been shown to interact with various cellular transcription factors and to belong to the nuclear histone acetyltransferase (HAT) family. To further elucidate the function of Tip60 and its HAT domain in transcription regulation, we compared Tip60 activity in HeLa and Jurkat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to CD4 Antigens
Share to Gene Products, tat

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histone Acetyltransferases

Share to HIV Long Terminal Repeat

Share to Jurkat Cells

Share to Two-Hybrid System Techniques

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Identifiers

PMID: 11275565
DOI: 10.1093/oxfordjournals.jbchem.a002901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tip60 is a cell-type-specific transcriptional regulator.PMID 11275565Read ↗

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoterSemantic proximity Read ↗

Tip60 is a co-activator specific for class I nuclear hormone receptors.Semantic proximity Read ↗

Identification of a Cellular Protein That Specifically Interacts with the Essential Cysteine Region of the HIV-1 Tat TransactivatorSemantic proximity Read ↗

Homozygous disruption of the Tip60 gene causes early embryonic lethality.Semantic proximity Read ↗

Tip60 acetyltransferase activity is controlled by phosphorylation.Semantic proximity Read ↗

The multitalented TIP60 chromatin remodeling complex: wearing many hats in epigenetic regulation, cell division and diseasesSemantic proximity Read ↗

The histone acetyltransferase TIP60 interacts with c-Myb and inactivates its transcriptional activity in human leukemia.Semantic proximity Read ↗

TIP60 inhibits metastasis by ablating DNMT1−SNAIL2-driven epithelial-mesenchymal transition programSemantic proximity Read ↗

The TIP60 Complex Is a Conserved Coactivator of HIF1ASemantic proximity Read ↗

Destabilization of TIP60 by Human Papillomavirus E6 Results in Attenuation of TIP60-Dependent Transcriptional Regulation and Apoptotic PathwaySemantic proximity Read ↗

The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repairSemantic proximity Read ↗

HIV-1 Tat Protein-mediated Transactivation of the HIV-1 Long Terminal Repeat Promoter Is Potentiated by a Novel Nuclear Tat-interacting Protein of110 kDa, Tip110Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.