Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted inactivation of Gh/tissue transglutaminase II.

The Journal of biological chemistry - 8 Jun 2001

Nanda N, Iismaa S E, Owens W A, Husain A, Mackay F, Graham R M

Abstract excerpt

The novel G-protein, G(h)/tissue transglutaminase (TGase II), has both guanosine triphosphatase and Ca(2+)-activated transglutaminase activity and has been implicated in a number of processes including signal transduction, apoptosis, bone ossification, wound healing, and cell adhesion and spreadi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Integrases
Share to Mice, Knockout
Share to Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Sequence

Share to DNA Primers

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Transglutaminases

Share to Viral Proteins

Source

Identifiers

PMID: 11274171
DOI: 10.1074/jbc.M010846200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11274171-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted inactivation of Gh/tissue transglutaminase II.PMID 11274171Read ↗

Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.Semantic proximity Read ↗

Targeted expression of activated Q227L G(alpha)(s) in vivo.Semantic proximity Read ↗

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation.Semantic proximity Read ↗

Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression.Semantic proximity Read ↗

Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles.Semantic proximity Read ↗

COX-2-dependent cardiac failure in Gh/tTG transgenic mice.Semantic proximity Read ↗

Ablation of Egr2-positive cells in male mouse anterior pituitary leads to atypical isolated GH deficiency.Semantic proximity Read ↗

Discovery of Glucocorticoid Receptor-β in Mice with a Role in MetabolismSemantic proximity Read ↗

Alpha1B-adrenoceptor signaling and cell motility: GTPase function of Gh/transglutaminase 2 inhibits cell migration through interaction with cytoplasmic tail of integrin alpha subunits.Semantic proximity Read ↗

External GTP-bound transglutaminase 2 is a molecular switch for chondrocyte hypertrophic differentiation and calcification.Semantic proximity Read ↗

Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity.Semantic proximity Read ↗

Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.