Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interruption of the cydB locus in Brucella abortus attenuates intracellular survival and virulence in the mouse model of infection.

Journal of bacteriology - 1 Apr 2001

Endley S, McMurray D, Ficht T A

Abstract excerpt

Brucellosis is characterized by abortion in ruminants and a protracted undulant fever in humans, which often results in severe pathological manifestations. Scant information exists about the molecular mechanisms employed by Brucella abortus to combat host defenses or to persist and replicate within host cells. Transposon (Tn5) mutagenesis of B. abortus and the subsequent screening of mutants for sensitivity to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brucella abortus
Share to Brucellosis
Share to Cytochrome b Group

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytochromes

Share to DNA Transposable Elements

Share to Electron Transport Chain Complex Proteins

Share to Oxidoreductases

Share to Transformation, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 11274104
DOI: 10.1128/JB.183.8.2454-2462.2001
PMCID: PMC95161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interruption of the cydB locus in Brucella abortus attenuates intracellular survival and virulence in the mouse model of infection.PMID 11274104Read ↗

The Brucella abortus Cu,Zn superoxide dismutase is required for optimal resistance to oxidative killing by murine macrophages and wild-type virulence in experimentally infected mice.Semantic proximity Read ↗

A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen speciesSemantic proximity Read ↗

A putative xanthine dehydrogenase protects <i>Borrelia burgdorferi</i> from reactive oxygen species and promotes virulenceSemantic proximity Read ↗

sodA is essential for virulence of Borrelia burgdorferi in the murine model of Lyme disease.Semantic proximity Read ↗

Novel role for the yceGH tellurite resistance genes in the pathogenesis of Bacillus anthracis.Semantic proximity Read ↗

Brucella abortus nicotinamidase (PncA) contributes to its intracellular replication and infectivity in mice.Semantic proximity Read ↗

Construction of Cu-Zn superoxide dismutase deletion mutants of Brucella abortus: analysis of survival in vitro in epithelial and phagocytic cells and in vivo in mice.Semantic proximity Read ↗

Periplasmic superoxide dismutase in meningococcal pathogenicity.Semantic proximity Read ↗

Contribution of the Mn-cofactored superoxide dismutase (SodA) to the virulence of Yersinia enterocolitica serotype O8.Semantic proximity Read ↗

An iron-acquisition-deficient mutant of Corynebacterium pseudotuberculosis efficiently protects mice against challenge.Semantic proximity Read ↗

Brucella abortusd-alanyl-D-alanine carboxypeptidase contributes to its intracellular replication and resistance against nitric oxide.Semantic proximity Read ↗

Nitrosative damage to free and zinc‐bound cysteine thiols underlies nitric oxide toxicity in wild‐type Borrelia burgdorferiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.