Article
An iron-acquisition-deficient mutant of Corynebacterium pseudotuberculosis efficiently protects mice against challenge.
Veterinary research - 6 Mar 2014
Ribeiro Dayana, Rocha Flávia de Souza, Leite Kátia Morais Costa, Soares Siomar de Castro, Silva Artur, Portela Ricardo Wagner Dias, Meyer Roberto, Miyoshi Anderson, Oliveira Sérgio Costa, Azevedo Vasco, Dorella Fernanda Alves
Abstract excerpt
Caseous lymphadenitis (CLA) is a chronic disease that affects sheep and goats worldwide, and its etiological agent is Corynebacterium pseudotuberculosis. Despite the economic losses caused by CLA, there is little information about the molecular mechanisms of bacterial pathogenesis, and current immune prophylaxis against infection has been unable to reduce the incidence of CLA in goats. Recently, 21 different...
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