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Article

Novel role for the yceGH tellurite resistance genes in the pathogenesis of Bacillus anthracis.

Infection and immunity - 1 Mar 2014

Franks Sarah E, Ebrahimi Celia, Hollands Andrew, Okumura Cheryl Y, Aroian Raffi V, Nizet Victor, McGillivray Shauna M

Abstract excerpt

Bacillus anthracis, the causative agent of anthrax, relies on multiple virulence factors to subvert the host immune defense. Using Caenorhabditis elegans as an infection model, we screened approximately 5,000 transposon mutants of B. anthracis Sterne for decreased virulence. One of the attenuated mutants resulted in loss of expression of yceG and yceH, the last two genes in a six-gene cluster of tellurite...

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Identifiers

PMID: 24366250
DOI: 10.1128/IAI.01614-13
PMCID: PMC3957989

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Source receipt: pubmed, retrieved 7 Sept 2026.

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