Article
Modulation of contractile activation in skeletal muscle by a calcium-insensitive troponin C mutant.
The Journal of biological chemistry - 8 Jun 2001
Morris C A, Tobacman L S, Homsher E
Abstract excerpt
Calcium controls the level of muscle activation via interactions with the troponin complex. Replacement of the native, skeletal calcium-binding subunit of troponin, troponin C, with mixtures of functional cardiac and mutant cardiac troponin C insensitive to calcium and permanently inactive provid...
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