Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.

Leukemia research - 1 Mar 2000

Inoue K, Kohno T, Takakura S, Hayashi Y, Mizoguchi H, Yokota J

Abstract excerpt

Allelic status of the BAT26 and BAT25 loci was examined in 117 leukemia/lymphoma cell lines consisting of 44 B-lymphoid lineage cell lines, 30 T-lymphoid cell lines and 43 myeloid cell lines to define the lineage specificity of microsatellite instability (MSI) in hematological malignancies. Seventeen (15%) cell lines were defined as having MSI. The incidence of MSI was significantly (P < 0.01) higher in cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to bcl-2-Associated X Protein
Share to Gene Frequency
Share to Leukemia-Lymphoma, Adult T-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microsatellite Repeats

Share to Mutation

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins c-bcl-2

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 10739008
DOI: 10.1016/s0145-2126(99)00182-4

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.PMID 10739008Read ↗

Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.Semantic proximity Read ↗

Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability.Semantic proximity Read ↗

Hematopoietic malignancies demonstrate loss-of-function mutations of BAX.Semantic proximity Read ↗

Association of a novel single nucleotide polymorphism, G(-248)A, in the 5'-UTR of BAX gene in chronic lymphocytic leukemia with disease progression and treatment resistance.Semantic proximity Read ↗

Microsatellite instability is associated with the loss of apoptosis in ductal breast carcinomas.Semantic proximity Read ↗

Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias.Semantic proximity Read ↗

Role of bax mutations in apoptosis in colorectal cancers with microsatellite instability.Semantic proximity Read ↗

Role ofbaxMutations in Apoptosis in Colorectal Cancers With Microsatellite InstabilitySemantic proximity Read ↗

Somatic point mutations in the translocated bcl-2 genes of non-Hodgkin's lymphomas and lymphocytic leukemias: implications for mechanisms of tumor progression.Semantic proximity Read ↗

Infrequent bax gene mutations in B-cell lymphomas.Semantic proximity Read ↗

BAK, BAX, and NBK/BIK proapoptotic gene alterations in Iranian patients with ataxia telangiectasia.Semantic proximity Read ↗

Mutation of BAX occurs infrequently in acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.