Article
Sez4 gene encoding an elongation subunit of DNA polymerase zeta is required for normal embryogenesis.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Feb 2001
Kajiwara K, O-Wang J, Sakurai T, Yamashita S, Tanaka M, Sato M, Tagawa M, Sugaya E, Nakamura K, Nakao K, Katsuki M, Kimura M
Abstract excerpt
BACKGROUND: Sez4 identified as a seizure-activated gene shows a similarity to the yeast REV3 that encodes a catalytic subunit of the nonessential DNA polymerase zeta which is involved in error-prone translesion synthesis. Although yeast REV3 homologues in mouse and human have recently been identi...
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