Article
Clinical significance of mutator phenotype and chromosome 17p and 18q allelic loss in gastric cancer.
The British journal of surgery - 1 Mar 2001
de Manzoni G, Tomezzoli A, Di Leo A, Moore P S, Talamini G, Scarpa A
Abstract excerpt
BACKGROUND: Tumour stage is the only reliable prognostic factor for gastric cancer. The molecular anomalies involved in this process have the potential to serve as additional prognostic markers. METHODS: Forty-four gastric cancers, treated by surgery alone, have been analysed for chromosome 17p and 18q allelic loss and for the presence of microsatellite instability (MSI), using microsatellite markers and DNA from...
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