Article
EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye.
EMBO reports - 1 Feb 2001
Freeman M, Bienz M
Abstract excerpt
beta-catenin/Armadillo are transcriptional co-activators that mediate Wnt signalling in normal development. Activated forms of beta-catenin are oncogenic. We have constructed mutant forms of Drosophila Armadillo which correspond to common human oncogenic mutations, and find them to activate Armad...
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