Article
X inactivation of the OCNC1 channel gene reveals a role for activity-dependent competition in the olfactory system.
Cell - 9 Mar 2001
Zhao H, Reed R R
Abstract excerpt
The organization of neuronal systems is often dependent on activity and competition between cells. In olfaction, the X-linked OCNC1 channel subunit is subject to random inactivation and is essential for odorant-evoked activity. Reporter-tagged OCNC1 mutant mice permit the visualization of OCNC1-deficient olfactory neurons and their projections. In heterozygous females, X inactivation creates a mosaic with two...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.