Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mice deficient in G(olf) are anosmic.

Neuron - 1 Jan 1998

Belluscio L, Gold G H, Nemes A, Axel R

Abstract excerpt

We have used gene targeting to examine the role of the G alpha subunit, G(olf), in olfactory signal transduction. Mice homozygous for a null mutation in G(olf) show a striking reduction in the electrophysiological response of primary olfactory sensory neurons to a wide variety of odors. Despite this profound diminution in response to odors, the topographic map of primary sensory projections to the olfactory bulb...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Electrophysiology
Share to GTP-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Phenotype

Share to Reference Values

Share to Signal Transduction

Source

Identifiers

PMID: 9459443
DOI: 10.1016/s0896-6273(00)80435-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mice deficient in G(olf) are anosmic.PMID 9459443Read ↗

Impaired olfactory behavior in mice deficient in the alpha subunit of G(o).Semantic proximity Read ↗

Gain-of-function mutation in Gnao1: a murine model of epileptiform encephalopathy (EIEE17)?Semantic proximity Read ↗

Lgl1 Is Required for Olfaction and Development of Olfactory Bulb in Mice.Semantic proximity Read ↗

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in miceSemantic proximity Read ↗

The genetics of olfaction.Semantic proximity Read ↗

Characterization of mice with cell type-specific <i>Gnal</i> loss of function provides insights on <i>GNAL</i> -linked dystoniaSemantic proximity Read ↗

Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulbSemantic proximity Read ↗

Sex-dependent behavioral functions of the Purkinje cell-specific Gαi/o binding protein, Pcp2(L7).Semantic proximity Read ↗

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia.Semantic proximity Read ↗

Mutated olfactomedin 1 in the interphotoreceptor matrix of the mouse retina causes functional deficits and vulnerability to light damage.Semantic proximity Read ↗

Amino acids involved in conformational dynamics and G protein coupling of an odorant receptor: targeting gain-of-function mutation.Semantic proximity Read ↗

Olfaction in Drosophila: from odor to behavior.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.